NPR Podcast Directory
http://www.npr.org/rss/podcast/podcast_directory.php

Talk of the Nation - Science Friday
Two hours of science topics ever Friday that are presented in a non-science-y way:
http://www.sciencefriday.com/audio/scifriaudio.xml

Lichtenstein Creative Media
Creating Media that Matters – producer of public television and radio programs and documentary films.
LCM Productions:  The Infinite Mind  State of Mind   Voices of an Illness (and more)

To the Point
M-Friday hour-long news show with guests:
http://kcrw.com/podcast/show/tp

Left, Right, and Center
30 min. weekly show that covers all areas of the political spectrum but no one gets nasty:  http://ax.phobos.apple.com.edgesuite.net/WebObjects/MZStore.woa/wa/podcastRSS?id=73329771

The Slate Explainer4 or 5 minute daily explanation of topics like “Does Dick Cheney Know How to Hunt?”
http://www.slate.com/podcast/id/2129874/